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  1. Pilot trial of risk-adapted cyclophosphamide intensity based conditioning and HLA matched sibling and unrelated cord blood stem cell transplantation in newly diagnosed pediatric and adolescent recipients with acquired severe aplastic anemia

    ...

    Research Article last updated 04/09/2014 - 9:11am.

  2. Acceptable HLA-mismatching in unrelated donor bone marrow transplantation for patients with acquired severe aplastic anemia

    ... We retrospectively analyzed the impact of HLA mismatching (HLA-A, -B, -C, -DRB1, -DQB1) using molecular typing on transplant outcome for ...

    Research Article last updated 10/11/2011 - 5:58pm.

  3. Alternative donor transplantation for aplastic anemia.

    ... who do not have a human leukocyte antigen ( HLA )-identical sibling generally receive immunosuppressive therapy as a ... of Caucasian descent will have an available and fully HLA-matched unrelated adult donor; the rate is substantially lower for ...

    Research Article last updated 10/11/2011 - 5:58pm.

  4. Granulocyte transfusions in severe aplastic anemia: an eleven-year experience.

    ... absolute neutrophil count, stratified by HLA alloimmunization status. RESULTS: Thirty-two patients with ... A. One quarter of patients had demonstrable HLA alloimmunization prior to the initiation of granulocyte therapy. ... neutrophil count between the patients divided according to HLA alloimmunization status. CONCLUSIONS: Granulocyte transfusions ...

    Research Article last updated 10/11/2011 - 5:58pm.

  5. Drug reduces acute GVHD in unrelated HSCTs

    ... myeloablative HSCT was appropriate were paired with 8/8 HLA -A, -B, -C unrelated donors. GVHD prophylaxis consisted of intravenous ...

    Article last updated 02/27/2017 - 1:45pm.

  6. Biparental HLA Haplotype Disparate T-cell Depleted Transplants for Patients Lacking an HLACompatible Donor

    ... for bone marrow transplants do not have an HLA -matched, or close to matched, donor available. For this reason, doctors have been testing ways to make transplants from HLA-partially matched donors as safe and effective as transplants from ...

    Clinical Trial last updated 04/29/2016 - 1:59pm.

  7. Contribution of Revised International Prognostic Scoring System Cytogenetics to Predict Outcome After Allogeneic Stem Cell Transplantation for Myelodysplastic Syndromes: A Study From the French Society of Bone Marrow Transplantation and Cellular Therapy

    ... on the outcome of 367 MDS patients transplanted from HLA -identical siblings or HLA allele-matched unrelated donors. RESULTS: According to the ...

    Research Article last updated 04/08/2015 - 9:59am.

  8. Non-myeloablative peripheral blood haploidentical stem cell transplantation for refractory severe aplastic anemia

    ... Graft failure was associated with donor-directed HLA antibodies, despite intensive pre-HSCT desensitization with plasma ... rescue refractory SAA patients who lack donor-directed HLA antibodies but not in the presence of donor-directed HLA antibodies. This ...

    Research Article last updated 08/04/2014 - 8:20am.

  9. Haploidentical transplantation for pediatric patients with acquired severe aplastic anemia

    ... alternative therapy for pediatric SAA patients without HLA -matched sibling donors. Bone Marrow ...

    Research Article last updated 01/24/2017 - 11:52am.

  10. First-line treatment for severe aplastic anemia in children: bone marrow transplantation from a matched family donor vs. immunosuppressive therapy

    ... underwent bone marrow transplantation from an HLA -matched family donor registered in the Japan Society for Hematopoietic ... anemia received bone marrow transplantation from an HLA-matched family donor (n=213) or immunosuppressive therapy (n=386) as ...

    Research Article last updated 09/24/2014 - 10:16am.