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  1. Allogeneic transplant: does age still matter?

    ... of reduced or nonmyeloablative regimens, and improved HLA matching. Despite an increase in unrelated donor availability, ...

    Article last updated 08/31/2017 - 2:17pm.

  2. Pilot trial of risk-adapted cyclophosphamide intensity based conditioning and HLA matched sibling and unrelated cord blood stem cell transplantation in newly diagnosed pediatric and adolescent recipients with acquired severe aplastic anemia

    Journal Title:  Pediatr Blood Cancer Primary Author:  McGuinn C Author(s):  M...

    Research Article last updated 04/09/2014 - 9:11am.

  3. Acceptable HLA-mismatching in unrelated donor bone marrow transplantation for patients with acquired severe aplastic anemia

    ... We retrospectively analyzed the impact of HLA mismatching (HLA-A, -B, -C, -DRB1, -DQB1) using molecular typing on transplant outcome for ...

    Research Article last updated 10/11/2011 - 5:58pm.

  4. Alternative donor transplantation for aplastic anemia.

    ... who do not have a human leukocyte antigen ( HLA )-identical sibling generally receive immunosuppressive therapy as a ... of Caucasian descent will have an available and fully HLA-matched unrelated adult donor; the rate is substantially lower for ...

    Research Article last updated 10/11/2011 - 5:58pm.

  5. Granulocyte transfusions in severe aplastic anemia: an eleven-year experience.

    ... absolute neutrophil count, stratified by HLA alloimmunization status. RESULTS: Thirty-two patients with ... A. One quarter of patients had demonstrable HLA alloimmunization prior to the initiation of granulocyte therapy. ... neutrophil count between the patients divided according to HLA alloimmunization status. CONCLUSIONS: Granulocyte transfusions ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes

    ... MAC (n = 135) or RIC (n = 137) followed by HCT from HLA -matched related or unrelated donors. The primary end point was OS 18 ...

    Research Article last updated 05/02/2017 - 10:29am.

  7. Non-myeloablative peripheral blood haploidentical stem cell transplantation for refractory severe aplastic anemia

    ... Graft failure was associated with donor-directed HLA antibodies, despite intensive pre-HSCT desensitization with plasma ... rescue refractory SAA patients who lack donor-directed HLA antibodies but not in the presence of donor-directed HLA antibodies. This ...

    Research Article last updated 08/04/2014 - 8:20am.

  8. Contribution of Revised International Prognostic Scoring System Cytogenetics to Predict Outcome After Allogeneic Stem Cell Transplantation for Myelodysplastic Syndromes: A Study From the French Society of Bone Marrow Transplantation and Cellular Therapy

    ... on the outcome of 367 MDS patients transplanted from HLA -identical siblings or HLA allele-matched unrelated donors. RESULTS: According to the ...

    Research Article last updated 04/08/2015 - 9:59am.

  9. Effect of antithymocyte globulin source on outcomes of bone marrow transplantation for severe aplastic anemia

    ... aplastic anemia transplants between 2008 and 2013 using HLA -matched siblings (n=546) or unrelated donors (n=287) who received ... by type of antithymocyte globulin. Among recipients of HLA-matched sibling transplants, day 100 incidence of acute (17% versus 6%, ...

    Research Article last updated 04/14/2017 - 1:06pm.

  10. First-line treatment for severe aplastic anemia in children: bone marrow transplantation from a matched family donor vs. immunosuppressive therapy

    ... underwent bone marrow transplantation from an HLA -matched family donor registered in the Japan Society for Hematopoietic ... anemia received bone marrow transplantation from an HLA-matched family donor (n=213) or immunosuppressive therapy (n=386) as ...

    Research Article last updated 09/24/2014 - 10:16am.