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  1. HLA-Matched Sibling Transplantation for Severe Aplastic Anemia: Impact of HLA DR15 Antigen Status on Engraftment, Graft-versus-Host Disease, and Overall Survival.

    ... The HLA class II DRB1 antigen DR15 (common alleles *1501, *1502) is an ... aplastic anemia (SAA). We studied 1204 recipients of HLA-matched sibling bone marrow transplantation for SAA to determine ...

    Research Article last updated 06/15/2012 - 2:55pm.

  2. Frequent loss of HLA alleles associated with copy number-neutral 6pLOH in acquired aplastic anemia.

    ... commonly involved the human leukocyte antigen ( HLA ) locus, leading to loss of one HLA haplotype. Loss of HLA-A expression from multiple lineages of leukocytes ...

    Research Article last updated 10/12/2011 - 3:13pm.

  3. Stem Cell Transplantation From HLA Partially-Matched Related Donors for Patients With Hematologic Malignancies

    ... (HSCT) from Human Leukocyte Antigen ( HLA )-mismatched related donors for children and young adults with ... Available related donor who is mismatched at ≥ 2 HLA alleles Exclusion Criteria:  Available HLA -identical related donor HIV positive Active uncontrolled ...

    Clinical Trial last updated 04/29/2016 - 10:59am.

  4. Allogeneic transplant: does age still matter?

    ... of reduced or nonmyeloablative regimens, and improved HLA matching. Despite an increase in unrelated donor availability, ...

    Article last updated 08/31/2017 - 2:17pm.

  5. Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes

    ... MAC (n = 135) or RIC (n = 137) followed by HCT from HLA -matched related or unrelated donors. The primary end point was OS 18 ...

    Research Article last updated 05/02/2017 - 10:29am.

  6. Effect of antithymocyte globulin source on outcomes of bone marrow transplantation for severe aplastic anemia

    ... aplastic anemia transplants between 2008 and 2013 using HLA -matched siblings (n=546) or unrelated donors (n=287) who received ... by type of antithymocyte globulin. Among recipients of HLA-matched sibling transplants, day 100 incidence of acute (17% versus 6%, ...

    Research Article last updated 04/14/2017 - 1:06pm.

  7. Current outcome of HLA identical sibling vs. unrelated donor transplants in severe aplastic anemia: an EBMT analysis

    Journal Title:  Haematologica Primary Author:  Bacigalupo A Author(s):  Bacig...

    Research Article last updated 03/02/2015 - 12:38pm.

  8. Pilot trial of risk-adapted cyclophosphamide intensity based conditioning and HLA matched sibling and unrelated cord blood stem cell transplantation in newly diagnosed pediatric and adolescent recipients with acquired severe aplastic anemia

    Journal Title:  Pediatr Blood Cancer Primary Author:  McGuinn C Author(s):  M...

    Research Article last updated 04/09/2014 - 9:11am.

  9. Drug reduces acute GVHD in unrelated HSCTs

    ... myeloablative HSCT was appropriate were paired with 8/8 HLA -A, -B, -C unrelated donors. GVHD prophylaxis consisted of intravenous ...

    Article last updated 02/27/2017 - 1:45pm.

  10. Acceptable HLA-mismatching in unrelated donor bone marrow transplantation for patients with acquired severe aplastic anemia

    ... We retrospectively analyzed the impact of HLA mismatching (HLA-A, -B, -C, -DRB1, -DQB1) using molecular typing on transplant outcome for ...

    Research Article last updated 10/11/2011 - 5:58pm.