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  1. Population pharmacokinetics of fludarabine in patients with aplastic anemia and Fanconi anemia undergoing allogeneic hematopoietic stem cell transplantation.

    ... with improved outcome in young patients with aplastic anemia (AA) and Fanconi anemia (FA), several factors limit the success of the procedure. We ...

    Research Article last updated 05/22/2017 - 10:32am.

  2. Resources to Help

    ... the life threatening hematological diseases; aplastic anemia , MDS and PNH. Medicaid – Prescription Drug Program ... ASOCIACIÓN ESPAÑOLA DE ANEMIA DE FANCONI Asociación de Hemoglobinuria Paroxística ...

    Topic section last updated 01/04/2018 - 2:11pm.

  3. Optimizing Cord Blood and Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502) (CHAMP)

    ... haploidentical transplantation for Severe Aplastic Anemia (SAA) patients. The primary objective is to assess overall survival ... failure syndromes. At minimum, the diagnosis of Fanconi anemia must be excluded by diepoxybutane (DEB) or equivalent ...

    Clinical Trial last updated 12/19/2017 - 7:55am.

  4. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... reduce transplant-related side effects for patients with Fanconi Anemia (FA). Patients will undergo a transplant utilizing mis-matched ... Criteria: Patients must have a diagnosis of Fanconi anemia Patients must have one of the following hematologic ...

    Clinical Trial last updated 05/09/2016 - 3:19pm.

  5. Late effects among pediatric patients followed for nearly 4 decades after transplantation for severe aplastic anemia

    ... Aplastic anemia (AA), a potentially fatal disease, may be cured with marrow ... years for the acquired AA patients is 82%, and for the Fanconi anemia patients it is 58% (P = .01). Multivariate analysis ...

    Research Article last updated 10/11/2011 - 5:58pm.

  6. Association between donor leukocyte telomere length and survival after unrelated allogeneic hematopoietic cell transplantation for severe aplastic anemia

    ... transplantation (HCT) for patients with severe aplastic anemia . DESIGN, PARTICIPANTS, AND SETTING: The study included 330 patients (235 acquired, 85 Fanconi anemia , and 10 Diamond-Blackfan anemia ) and their ...

    Research Article last updated 03/03/2015 - 11:48am.

  7. Somatic mutations identify a sub-group of aplastic anemia patients that progress to myelodysplastic syndrome

    ... Aplastic anemia (AA) is a heterogeneous disorder. The distinction between acquired ... who had stored BM and constitutional DNA. We excluded Fanconi anemia , mutations of telomere maintenance, and a family ...

    Research Article last updated 09/04/2014 - 11:05am.

  8. Genetic and epigenetic pathways in myelodysplastic syndromes: A brief overview

    ... is relatively higher in some genetic syndromes such as Fanconi anemia and receipt of chemotherapy and radiation treatment. In ...

    Research Article last updated 01/20/2015 - 12:59pm.

  9. Genomic analysis of bone marrow failure and myelodysplastic syndromes reveals phenotypic and diagnostic complexity

    ... sequencing. In patients with clinical diagnoses of Fanconi anemia , genomic analysis resolved subtype assignment, including those of ...

    Research Article last updated 10/02/2014 - 10:20am.

  10. HSCT for Patients With Fanconi Anemia Using Risk-Adjusted Chemotherapy (RAFA)

    ... cell transplant for the treatment of patients with Fanconi anemia and severe hematologic disease. Candidates for this trial will ...

    Clinical Trial last updated 04/28/2016 - 8:44am.