Relevance of prognostic factors in the decision-making of stem cell transplantation in Myelodysplastic Syndromes | Aplastic Anemia and MDS International Foundation

Relevance of prognostic factors in the decision-making of stem cell transplantation in Myelodysplastic Syndromes

Journal Title: 
Rev Assoc Med Bras
Primary Author: 
Duarte FB
Author(s): 
Duarte FB, Santos TE, Barbosa MC, Kaufman J, Vasconcelos JP, Lemes RP, Rocha FD, Coutinho DF, Zalcberg I, Vasconcelos PR
Original Publication Date: 
Saturday, October 1, 2016

The hematopoietic stem cell transplantation (HSCT) is the only curative alternative for Myelodysplastic Syndrome (MDS), but many patients are not eligible for this treatment, as there are several limiting factors, especially in the case of patients with low-risk MDS. The aim of this study is to discuss the factors that can guide the decision-making on referring or not a patient to HSCT. Three cases of MDS, two of which were submitted to HSCT are presented. We intend to report the difficulties in referring patients with MDS to transplant and the prognostic factors that contribute to define eligibility.

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