Bone Marrow Transplantation for Acquired Severe Aplastic Anemia | Aplastic Anemia and MDS International Foundation

Bone Marrow Transplantation for Acquired Severe Aplastic Anemia

Journal Title: 
Hematol Oncol Clin North Am
Author(s): 
Bacigalupo A
Primary Author: 
Bacigalupo A
Original Publication Date: 
Monday, December 15, 2014

This article addresses current transplant options for patients with acquired severe aplastic anemia (SAA). This discussion includes ongoing progress in the use of SAA in the setting of unrelated donor transplants, which now provide outcomes similar, though still not identical, to HLA-identical sibling transplants. Recent data on stem cell source, conditioning regimens, and graft-versus-host disease prophylaxis are outlined. Other donor types such as cord blood and haploidentical mismatched family donors are also discussed.

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