Recent Research Information on Aplastic Anemia, MDS, and PNH

AA&MDSIF strives to keep patients, families, and hematology/oncology professionals up-to-date with developments in research and practice relevant to aplastic anemia, MDS and PNH. Shown below are recent articles from major hematology/oncology journals, retrieved from the National Library of Medicine’s PubMed portal to their MEDLINE database of journal citations and abstracts of the biomedical literature from around the world.


Looking for research oriented for patients and caregivers? For select reviews of important medical journal articles, written by hematology/oncology professionals, visit Research Reviews for Patients. These reviews interpret the most relevant information for patients from the latest published research.

You can also read Research Summaries for Patients that are lay language explanations of scientific meetings and symposia.

Summary information is listed by publication date, title, journal title and senior author. By default, the articles are listed by their publication date in reverse chronological order, from the most recent article to oldest article. Clicking the date column heading will sort them the other way, from oldest to newest.

"Publication date" in most cases means when the article first appeared in the electronic/online issue of a journal, in advance of when it appears in the print journal. Keep in mind some articles may appear online months before appearing in print, and that some may be from online-only journals.

You can also alphabetically and reverse alphabetically sort articles, primary authors and journal titles by clicking their column heading. To find articles by disease type, choose it from the drop-down menu named "Filter by Disease", and only articles about those diseases will appear. The search box labeled “Filter by Search Term” lets you search for a word in the article title, author, or journal name.

When you open an article citation by clicking on the title, article summary information (this time including all authors) is again shown, and in most cases you can view the article abstract. In some cases the abstract is unavailable, and not shown. You can also progress to the article’s PubMed entry by clicking the PubMed ID number link, shown directly under the title. Here you can purchase the article for download viewing or view through your institutional library’s access. In some cases, full text viewing is free either from the publisher’s site or from PubMed Central, an searchable aggregation site of free full text articles.

The PubMed Web site has extensive features, along with help tools and links to other databases. Regular users are encouraged to become familiar with its many capabilities.

Publication Date Article Title Journal Title Primary Authorsort icon Bone Marrow Disease(s)
10/14/2012 Last Marrow Standing: Bone Marrow Transplantation for Acquired Bone Marrow Failure Conditions Curr Hematol Malig Rep Gerds AT myelodysplastic syndromes (MDS)
01/01/2010 High-risk myelodysplastic syndromes: chemotherapy, transplantation, and beyond. Curr Hematol Malig Rep Gergis U myelodysplastic syndromes (MDS)
07/26/2013 Syngeneic transplantation in aplastic anemia: pretransplant conditioning and peripheral blood are associated with improved engraftment - an observational study on behalf of the Severe Aplastic Anemia and Pediatric Diseases Working Parties of the European Haematologica Gerull S aplastic anemia
05/10/2014 Outcomes in RBC transfusion-dependent patients with Low-/Intermediate-1-risk myelodysplastic syndromes with isolated deletion 5q treated with lenalidomide: a subset analysis from the MDS-004 study Eur J Haematol Giagounidis A myelodysplastic syndromes (MDS)
09/10/2013 Lenalidomide as a disease-modifying agent in patients with del(5q) myelodysplastic syndromes: linking mechanism of action to clinical outcomes. Ann Hematol Giagounidis A myelodysplastic syndromes (MDS)
10/01/2012 Lenalidomide for del(5q) and Non-del(5q) Myelodysplastic Syndromes Semin Hematol Giagounidis AA myelodysplastic syndromes (MDS)
03/01/2013 High levels of vascular endothelial growth factor protein expression are associated with an increased risk of transfusion dependence in myelodysplastic syndromes Am J Clin Pathol Gianelli U myelodysplastic syndromes (MDS)
01/10/2011 Review of stem-cell transplantation for myelodysplastic syndromes in older patients in the context of the Decision Memo for Allogeneic Hematopoietic Stem Cell Transplantation for Myelodysplastic Syndrome emanating from the Centers for Medicare & Medicaid J Clin Oncol Giralt SA myelodysplastic syndromes (MDS)
01/01/2014 Pediatric myelodysplastic syndromes: they do exist! J Pediatr Hematol Oncol Glaubach T myelodysplastic syndromes (MDS)
07/05/2014 An exploratory phase 2 study of investigational Aurora A kinase inhibitor alisertib (MLN8237) in acute myelogenous leukemia and myelodysplastic syndromes Leuk Res Rep Goldberg SL myelodysplastic syndromes (MDS)