Grant Recipients | Page 4 | Aplastic Anemia and MDS International Foundation

Grant Recipients

For nearly 30 years, AAMDSIF has provided research grants totaling in excess of $4 million to an international group of more than 75 researchers to help advance the understanding and treatment of aplastic anemia, myelodysplastic syndromes (MDS), and paroxysmal nocturnal hemoglobinuria (PNH).

The two-year grants have helped bring forth new insights into the causes and therapeutic approaches for these diseases. These grantee profiles present the grantees by year the awards were granted, and a summary of their grant-funded research projects.

View a single grant year.

Grant Year: 2011

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Kim-Hien T. Dao, DO, PhD

Torry Yahn Research Fund

Dr. Dao will investigate why the blood stem cells from patients who inherit a loss-of-function mutation in one of the genes of the Fanconi anemia pathway are highly susceptible to cell death yet also highly susceptible to conversion into an acute leukemia.

Keith McCrae, MD

PNH Research and Support Foundation

Dr. McCrae's study explores why patients with PNH are at increased risk for the development of thrombosis, or blood clots, that may affect arteries or veins and cause events such as pulmonary emboli or stroke.
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Parinda Mehta, MD

Trinity Ewert Research Fund

Dr. Mehta will study the use of Quercetin, a naturally occurring flavonoid (antioxidant) in patients with Fanconi anemia, one of the most common congenital bone marrow failure syndromes. She anticipates that the results of this pilot study will show that long term oral Quercetin therapy is feasible and well tolerated in patients with Fanconi anemia. These results will form the basis of the continuation phase of the study, which will demonstrate that Quercetin therapy in fact delays or prevents progressive marrow failure in children with Fanconi anemia.
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Mridul Mukherji, DPhil

Harold Spielberg Research Fund

TET2 is one of the most frequently mutated genes identified in patients with myelodysplastic syndromes (MDS). This study will help explore new avenues for the cure TET2 mutations, and Dr. Mukherji says he and his colleagues “will use our expertise to develop strategies to restore TET2 activity for the treatment of MDS.”

Grant Year: 2010

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Gregory Abel, MD

MacGillivray Research Fund , Madden Family Research Fund

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Cristian Bellodi, PhD

Emily Kass Research Fund

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Muneyoshi Futami, MD, PhD

Harold Spielberg Research Fund

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Ramon V. Tiu, MD

Torry Yahn Research Fund

Grant Year: 2009

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Regis Peffault deLatour, MD, PhD

PNH Research and Support Foundation

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Archibald S. Perkins, MD, PhD

Harold Spielberg Research Fund