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Research Articles

Compiled for your convenience are articles on bone marrow failure research and treatment from the world’s major journals on hematology / oncology.

Article Title Original Publication Date Journal Bone Marrow Disease
Persistent elevation of plasma thrombopoietin levels after treatment in severe aplastic anemia Sep 2017 Exp Hematol aplastic anemia
Personalized medicine in myelodysplastic syndromes: wishful thinking or already clinical reality? May 2015 Haematologica myelodysplastic syndromes (MDS)
Pexmetinib: a novel dual inhibitor of Tie-2 and p38 MAPK with efficacy in preclinical models of myelodysplastic syndromes and acute myeloid leukemia Jun 2016 Cancer Res. myelodysplastic syndromes (MDS)
Phase 2 Study of the ALK5 Inhibitor Galunisertib in Very Low-, Low-, and Intermediate-Risk Myelodysplastic Syndromes Sep 2019 Clinical Cancer Research: an official Journal of the American Association of Cancer Research myelodysplastic syndromes (MDS)
Phase 2 study of the lenalidomide and azacitidine combination in patients with higher-risk myelodysplastic syndromes. Aug 2012 Blood myelodysplastic syndromes (MDS)
Phase 2, randomized, double-blind study of pracinostat in combination with azacitidine in patients with untreated, higher risk myelodysplastic syndromes Jan 2017 Cancer myelodysplastic syndromes (MDS)
Phase I trial of SAR103168, a novel multi-kinase inhibitor,in patients with refractory/relapsed acute leukemias or high-risk myelodysplastic syndromes May 2014 Leuk Lymphoma myelodysplastic syndromes (MDS)
Phase II clinical study of erlotinib for treatment of myelodysplastic syndromes Apr 2014 Am J Hematol myelodysplastic syndromes (MDS)
Phase II study of the clinical efficacy and safety of tosedostat in patients with myelodysplastic syndromes (MDS) after failure of hypomethylating agent-based therapy Oct 2020 Leukemia & Lymphoma myelodysplastic syndromes (MDS)
Phase II trials of zilucoplan in paroxysmal nocturnal hemoglobinuria Aug 2023 Haematologica paroxysmal nocturnal hemoglobinuria (PNH)
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