Recent Research

Compiled for your convenience are the latest articles on bone marrow failure research and treatment from the world’s major journals on hematology / oncology. Articles are obtained from the National Library of Medicine’s MEDLINE database and date back to 2010.

Article Title Original Publication Date Journal Bone Marrow Disease
Pexmetinib: a novel dual inhibitor of Tie-2 and p38 MAPK with efficacy in preclinical models of myelodysplastic syndromes and acute myeloid leukemia Jun 2016 Cancer Res. myelodysplastic syndromes (MDS)
Bone marrow transplantation versus immunosuppressive therapy in patients with acquired severe aplastic anemia Jun 2016 Int J Hematol aplastic anemia
Mutational hierarchies in myelodysplastic syndromes dynamically adapt and evolve upon therapy response and failure Jun 2016 Blood myelodysplastic syndromes (MDS)
Comparison of Intensive Chemotherapy and Hypomethylating Agents before Allogeneic Stem Cell Transplantation for Advanced Myelodysplastic Syndromes: A Study of the Myelodysplastic Syndrome Subcommittee of the Chronic Malignancies Working Party of the Europ Jun 2016 Biol Blood Marrow Transplant myelodysplastic syndromes (MDS)
Integrating Frailty, Comorbidity, and Quality of Life in the Management of Myelodysplastic Syndromes Jun 2016 Am Soc Clin Oncol Educ Book myelodysplastic syndromes (MDS)
Searching for a Light at the End of the Tunnel? Beyond Hypomethylating Agents in Myelodysplastic Syndromes Jun 2016 Am Soc Clin Oncol Educ Book myelodysplastic syndromes (MDS)
Efficacy and safety of darbepoetin alpha in patients with myelodysplastic syndromes: a systematic review and meta-analysis May 2016 Br J Haematol myelodysplastic syndromes (MDS)
Effectiveness of azacitidine in higher-risk myelodysplastic syndromes May 2016 Leukemia myelodysplastic syndromes (MDS)
Design and rationale of the QUAZAR Lower-Risk MDS (AZA-MDS-003) trial: a randomized phase 3 study of CC-486 (oral azacitidine) plus best supportive care vs placebo plus best supportive care in patients with IPSS lower-risk myelodysplastic syndromes and po May 2016 BMC Hematol myelodysplastic syndromes (MDS)
Long-term issues after Immunosuppressive therapy for Aplastic Anemia May 2016 Curr Drug Targets aplastic anemia