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aplastic anemia

Short telomeres: from dyskeratosis congenita to sporadic aplastic anemia and malignancy.

Author(s): 
Gramatges MM, Bertuch AA.
Primary Author: 
Gramatges MM
Journal Title: 
Transl Res
Original Publication Date: 
Jun 2013

Telomeres are DNA-protein structures that form a protective cap on chromosome ends. As such, they prevent the natural ends of linear chromosomes from being subjected to DNA repair activities that would result in

Bone Marrow Diseases: 

Therapeutic targeting of NOTCH signaling ameliorates immune-mediated bone marrow failure of aplastic anemia.

Author(s): 
Roderick JE, Gonzalez-Perez G, Kuksin CA, Dongre A, Roberts ER, Srinivasan J, Andrzejewski C Jr, Fauq AH, Golde TE, Miele L, Minter LM.
Primary Author: 
Roderick JE
Journal Title: 
J Exp Med
Original Publication Date: 
Jun 2013

Severe

Bone Marrow Diseases: 

Aplastic Anemia & MDS International Foundation: Bone marrow failure disease scientific symposium 2012

Author(s): 
Savage SA, Pulsipher MA, Romano A, Berlyne D.
Primary Author: 
Savage SA
Journal Title: 
Leuk Res
Original Publication Date: 
May 2013

The decision to pursue hematopoietic stem cell transplantation or immunosuppression as first therapy in severe

Bone Marrow Diseases: 

Pathophysiology and management of thrombocytopenia in bone marrow failure: possible clinical applications of TPO receptor agonists in aplastic anemia and myelodysplastic syndromes.

Author(s): 
Townsley DM, Desmond R, Dunbar CE, Young NS.
Primary Author: 
Townsley DM
Journal Title: 
Int J Hematol
Original Publication Date: 
May 2013

Bone Marrow Diseases: 

Reduced dose cyclophosphamide, fludarabine and antithymocyte globulin for sibling and unrelated transplant of children with severe and very severe aplastic anemia.

Author(s): 
Chung NG, Lee JW, Jang PS, Jeong DC, Cho B, Kim HK
Primary Author: 
Chung NG
Journal Title: 
Pediatr Transplant
Original Publication Date: 
Apr 2013

We evaluated the results of a novel conditioning regimen of reduced dose

Bone Marrow Diseases: 

Less could be better: The case for reducing the dose of cyclophosphamide for children undergoing allogeneic stem cell transplant for severe aplastic anemia.

Author(s): 
Hussein AA, Frangoul H
Primary Author: 
Hussein AA
Journal Title: 
Pediatr Transplant
Original Publication Date: 
Apr 2013

No abstract available.

Bone Marrow Diseases: