Newsstand | Page 21 | Aplastic Anemia and MDS International Foundation

Newsstand

Here's where you'll find a regularly updated, broad range of articles written by the AAMDSIF team, allied health organizations and news organizations. By staying well-informed, patients and families are practicing a form of self-support that will help them be more effective self-advocates when engaging with health care providers.

New MDS Prognostic Scoring System May Lead to More Effective Treatment

Originally Published: 05/30/2012
The International Prognostic Scoring System (IPSS) is used by doctors to evaluate the seriousness of MDS in each patient.  It has prognostic value (i.e., predictive with respect to disease outcome) and will help to develop a treatment plan. One of the components of this scoring system is a genetic analysis.  This by itself allows 86% of all MDS patients to be classified in one of 3 groups (with either poor, intermediate or good prognosis).  However, 14% of MDS patients carry genetic abnormalities that cannot be classified with the current IPSS. In this study, 2,902 patients with either MDS...

Stem Cell Transplants May Be An Option for Some Elderly MDS Patients

Originally Published: 05/30/2012
Myelodysplastic Syndromes (MDS) is considered a disease of the hematopoietic (blood-forming) stem cells (HSCs) that are housed in the bone marrow.  Replacing diseased HSCs with healthy HSCs from healthy donors (through a procedure called allogeneic (i.e., not genetically related) bone marrow transplantation (aBMT)) is the only cure for MDS. In order to kill the diseased cells and to make space in the bone marrow so that transplanted healthy HSCs can be received, patients are “conditioned” prior to the actual transplant. This so-called “conditioning regimen” is unfortunately associated with a...