Iron Overload
Drugs that are considered standard and investigational therapies for iron overload are listed below, please click on their names for more information:
Generic Name | Brand Name |
deferasirox | (Exjade) |
Deferiprone is an iron chelator that removes excess iron from the body. Deferiprone is approved for use in Europe and is currently in Phase IV clinical trials for its use in patients with thalassemia for review by of the U.S. Food and Drug Administration. Deferiprone combines with iron in the bloodstream and both are removed from the body by the kidneys. Aplastic anemia, myelodysplastic syndromes (MDS), and paroxysmal nocturnal hemoglobinuria (PNH) patients are at risk for developing iron overload if they become dependent on blood transfusions. deferiprone
| (Ferriprox) |
Deferoxamine (Desferal) is an iron chelator, approved by the U.S. Food and Drug Administration (FDA) to remove excess iron from the body. Deferoxamine combines with iron in the bloodstream and is removed from the body by the kidneys. Aplastic anemia, myelodysplastic syndromes (MDS), and paroxysmal nocturnal hemoglobinuria (PNH) patients are at risk for developing iron overload if they become dependent on blood transfusions. desferrioxamine
| (Desferal) |
The information contained on these pages is not comprehensive. It should not be considered medical advice and does not take the place your physician's advice. Although AA&MDSIF strives to provide accurate and up-to-date information, it does not guarantee the accuracy or currency of this information.
